PopPK Auto-Diagnose

Upload PK data. The engine compares 8 structural models — 1/2/3-CMT × classical / monofractional / multifractional — and returns a verdict with statistical guardrails. Designed for DMPK leads who need a 2-minute diagnostic before opening a full population analysis.

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1 · Upload dataset

📂
Click or drag a CSV file
NONMEM-format expected (ID · TIME · DV · AMT · EVID)
▶ Accepted CSV format · click to expand

Required columns (case-insensitive, NONMEM aliases accepted):

  • TIME — time since dose. Aliases: time, t, tad, time_h, time_hr, tiempo, temps, zeit
  • DV — observed concentration. Aliases: dv, conc, concentration, y, obs, value, concentracion, konzentration, valeur

Optional columns: ID, AMT (dose), EVID (event ID), MDV (missing DV flag), RATE, DVID, CMT.

Header flexibility — punctuation, case, and parenthesised units are tolerated. Time (h), TIME_H, time-h and timeh all map to TIME. ES/FR/DE headers (tiempo, temps, zeit, etc.) are also accepted.

Minimum size: 4 distinct time points.

Example:

ID,TIME,DV,AMT,EVID
1,0,0,320,1
1,0.5,4.2,0,0
1,1,6.0,0,0
1,2,5.5,0,0
1,4,3.8,0,0
1,8,2.0,0,0
1,12,1.1,0,0
1,24,0.4,0,0

Do NOT submit datasets with direct identifiers (names, dates of birth, contact details). Use pseudonymised IDs.

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This report contains computational results. Pharmacological interpretation and clinical decisions are the responsibility of the client's expert team. FractaLPK does not provide medical, pharmacological, or regulatory advice.